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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53RK
All Species:
15.76
Human Site:
S226
Identified Species:
31.52
UniProt:
Q96S44
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96S44
NP_291028.3
253
28160
S226
E
A
F
L
K
S
Y
S
T
S
S
K
K
A
R
Chimpanzee
Pan troglodytes
XP_514697
253
28128
S226
E
A
F
L
K
S
Y
S
T
S
S
K
K
A
R
Rhesus Macaque
Macaca mulatta
XP_001107480
201
22218
R181
S
T
S
S
K
K
A
R
P
V
L
K
K
L
D
Dog
Lupus familis
XP_853966
302
33650
S275
E
A
F
L
K
S
Y
S
T
F
S
K
K
S
R
Cat
Felis silvestris
Mouse
Mus musculus
Q99PW4
244
27375
G217
E
A
F
L
K
S
Y
G
A
S
S
K
K
S
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425703
314
33606
A287
Q
A
L
L
Q
S
Y
A
A
A
S
K
K
S
G
Frog
Xenopus laevis
NP_001089506
237
26742
S210
R
L
L
L
Q
S
Y
S
S
T
S
K
K
S
G
Zebra Danio
Brachydanio rerio
NP_001018386
231
26056
S204
E
R
L
L
K
S
Y
S
S
A
S
K
K
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647948
224
25346
R196
E
H
V
L
A
A
Y
R
T
A
C
G
K
D
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002300825
226
25241
R199
D
R
I
L
A
G
Y
R
K
S
S
K
Q
W
S
Maize
Zea mays
NP_001146448
226
25230
R199
E
K
I
L
A
A
Y
R
K
A
S
K
Q
W
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53323
261
29918
F225
N
A
W
I
M
E
G
F
E
E
V
Y
R
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
68.3
78.4
N.A.
83.7
N.A.
N.A.
N.A.
56.3
66
61.2
N.A.
41.5
N.A.
N.A.
N.A.
Protein Similarity:
100
100
71.9
81.1
N.A.
88.9
N.A.
N.A.
N.A.
66.2
78.2
77.4
N.A.
56.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
86.6
N.A.
73.3
N.A.
N.A.
N.A.
46.6
46.6
60
N.A.
33.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
93.3
N.A.
80
N.A.
N.A.
N.A.
80
73.3
80
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
44.2
41.9
N.A.
N.A.
32.1
N.A.
Protein Similarity:
60.4
58.1
N.A.
N.A.
48.6
N.A.
P-Site Identity:
33.3
33.3
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
46.6
53.3
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
50
0
0
25
17
9
9
17
34
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% D
% Glu:
59
0
0
0
0
9
0
0
9
9
0
0
0
9
9
% E
% Phe:
0
0
34
0
0
0
0
9
0
9
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
9
9
0
0
0
9
0
0
17
% G
% His:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
50
9
0
0
17
0
0
84
75
0
0
% K
% Leu:
0
9
25
84
0
0
0
0
0
0
9
0
0
9
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% P
% Gln:
9
0
0
0
17
0
0
0
0
0
0
0
17
0
9
% Q
% Arg:
9
17
0
0
0
0
0
34
0
0
0
0
9
0
25
% R
% Ser:
9
0
9
9
0
59
0
42
17
34
75
0
0
42
25
% S
% Thr:
0
9
0
0
0
0
0
0
34
9
0
0
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
9
9
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
17
0
% W
% Tyr:
0
0
0
0
0
0
84
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _